Semiconductor Physics, Quantum Electronics & Optoelectronics, 20 (1), P. 129-136 (2017).

Differentiation of Mueller-matrix invariants of biological tissues fibrillar networks with different phase and amplitude anisotropy
A.G. Ushenko1, A.V. Dubolazov1, Yu.A. Ushenko1, L.Ya. Kushnerick1, M.Yu. Sakhnovskiy1, V.G. Zhytaryuk1, I. Lacusta1, O.G. Prydiy1, P. Grygorishin2

1Chernivtsi National University, 2, Kotsyubinsky str., 58012 Chernivtsi, Ukraine
2Bukovinian State Medical University, 58000 Chernivtsi, Ukraine; e-mail:

Abstract. The work is aimed at investigation of diagnostic efficiency of a new azimuthally stable Mueller-matrix method for analysis of laser autofluorescence coordinate distributions corresponding to biological tissue histological sections. A new model of generalized optical anisotropy observed in biological tissue protein networks has been proposed to study the processes of laser autofluorescence. The influence of complex mechanisms of both phase anisotropy (linear birefringence and optical activity) and linear (circular) dichroism has been taken into account. The interrelations between the azimuthally stable Mueller-matrix elements characterizing laser autofluorescence and different mechanisms of optical anisotropy have been ascertained. The statistic analysis of coordinate distributions inherent to these Mueller-matrix rotation invariants has been proposed. Thereupon the quantitative criteria (statistic moments of the 1st to 4th orders) of differentiation of histological sections of uterus wall tumor – group 1 (dysplasia) and group 2 (adenocarcinoma) have been found.

Keywords: fluorescent biopsy, biological tissues, malignant tumors of uterus.

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